Sixty-three cases of Lung Cancer were studied by brushing smears. We found a much higher frequencyof metaplasia in Squamous cell Ca. than inother types. The frequency of metaplasia in thecytologic groups of Squamous cell Ca. was 80% Metaplastic cells exhibit a round or rarely polygonaloutline. The Cytoplasma is eosinophillic, and the Nucleus is round and regular with. fine chromatinnetwork. These findings makee asy to distinguish itfrom Cancer cell, but it's very difficult to establichthe differential diagnosis between atypical metaplastic cell and Squamous cell Carcinoma. It mayprove possible to diagnose a pulmonary Cancer bymeans of a careful follow-up with cytologic examination.
The radiation effect on the Cancer can be recognized in smears. But definite classification ofirradiated benign cells and malignant ones is occasionally impossible.
