1972 年 11 巻 2 号 p. 231-235
To clarify a process of regeneration in the cervicalepithelia, special attention was accorded to thenature of mitotic cells. The regenerative process ofthe squamous epithelium was followed after chemicalor mechanical injuries to the cervix. The mechanism of regeneration and metaplasia of the columnar epithelium was studied by means of cryotherapy. Regeneration of both epithelia was performedby active proliferation of their epithelial cells. Priorto proliferation, these well differentiated cells undergo dedifferentiation from functional phase to proliferative phase. The morphological characteristics ofthe dedfferentiated cells were shown as those of regenerative cells. Some problems on proliferation anddifferentiation of the epithelial cells were discussedin connection with subepithelial connective tissue.
Mitotic form of the columnar cells and the originof the reserve cells were also discussed.