卵巣乳頭状嚢胞腺腫の境界病変の細胞診

抄録

A case of 15 year-old-girl with the ovarian papillary cystadenoma with borderline lesion was presented with special reference to the comparison between histology of the tumor and cytology of the cyst fluid incidentally obtained by peritoneal paracentesis.
The patient visited to the hospital because of increasing abdominal girth. The physical and laboratory examinations revealed the cystic tumor of left ovary and profuse ascites which contained a few clumps of slightly atypical columnar cells with occasional mutual inclusion in the cytological examination suggestive of borderline malignancy. At surgery, there were 7000ml of bloody ascites and the cystic tumor of left ovary with rupture. The cytological examination of the ascites at operation also showed several large groups of columnar cells with nuclear overlapping and variation in size. The pathological examination revealed the papillary cystadenoma with borderline lesion characterized by the noninvasive papillary growth of the cuboidal cells with single layer and considerable exfoliation of the tumor cells into the lumens and minimal nuclear abnormalities.
From the view of the pathological and surgical findings, it was inserpreted that the atypical cells detected in the initial ascites were derived from the detached tumor cells of papillary cystadenoma with borderline lesion. The cytological characteristics of the ovarian papillary cystadenoma with borderline lesion was described and further discussed in terms of the cytological difference between 4 cases of frank papillary cystadenocarcinoma of the ovary and our particular case.