For the purpose of obtaining the specific findings in cell features of early invasive squamous cell carcinoma of uterine cervix, 12 cases with squamous carcinoma in situ, 3 cases with possible invasive squamous cell carcinoma, 11 cases with early invasive squamous cell carcinoma and 9 cases with invasive squamous cell carcinoma were subjected to this study, and the smears taken by cotten swab from cervix or endocervix of these 35 cases were used as materials.
According to this study, it was concluded that, even in case the features of these malignant cells observed in early invasive squamous cell carcinoma may resemble those found in squamous carcinoma in situ, the cases where found were the findings such as a tendency of increasing of formation of cancer cell-cluster, existence of several tight and large clusters composed of over thirty malignant cells and other findings such as unevenly nuclear chromatin distribution of coarse granules, presence of distinct nucleoli, bleeding and tumor diathesis, may be strongly suggestive of early invasive squamous cell carcinoma of the uterine cervix.
