2001 年 40 巻 1 号 p. 89-90
Imprinting cytology using fresh brain materials obtained surgically from a 65-year male with a sparsely granulated pituitary adenoma revealed relatively large cells with inclusion bodies in the nuclei and severe pleomorphism. Other cells were small and round with granular cytoplasm and small granular nuclei. Immunohistochemically, growth hormone stained in cytoplasm and CAM 5.2 at the nuclear periphfery with a granular pattern, but findings for ACTH, PRH, CK, and EMA were negative. These findings on the brain species revealed a sparsely granulated adenoma of the pituitary gland, confirming the utility of cytologoly, in addition to histopathology, in diagnosing brain tumors.