日本臨床細胞学会雑誌
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
術中迅速捺印細胞診が有用であった高度異型性を示す下垂体腺腫
保坂 典子小林 明子櫻井 博文
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2001 年 40 巻 1 号 p. 89-90

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Imprinting cytology using fresh brain materials obtained surgically from a 65-year male with a sparsely granulated pituitary adenoma revealed relatively large cells with inclusion bodies in the nuclei and severe pleomorphism. Other cells were small and round with granular cytoplasm and small granular nuclei. Immunohistochemically, growth hormone stained in cytoplasm and CAM 5.2 at the nuclear periphfery with a granular pattern, but findings for ACTH, PRH, CK, and EMA were negative. These findings on the brain species revealed a sparsely granulated adenoma of the pituitary gland, confirming the utility of cytologoly, in addition to histopathology, in diagnosing brain tumors.

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