We report a case of squamous cell carcinoma (SCC) in the diverticulum of the urinary bladder. A 73-year-old women reported macroscopic hematuria. Voided urine cytology was negative. Image diagnosis revealed a diverticulum associated with an intradiverticular tumor.
Washing cytology of the urinary bladder showed a small number of cyanophilic cancer cells with dispersed chromatin distribution. Initial diagnosis was transitinal cell carcinoma. Retrospectively, however, a few orangeophilic cancer cells consistent with SCC were also found. The resected diverticulum showed a polypoid tumor that was a histologically pure form of keratinizing SCC involving the myometrium (NIT pT 2).
SCC accounts for about 20% of all neoplasia from the diverticulum of urinary bladder, and urine cytology is positive in most cases.