2003 年 42 巻 1 号 p. 96-97
A 78-year-old male reporting cough and hemoptysis was found in chest radiography to have multiple hazy nodular shadows in both lungs but computed tomography and ultrasonography did not indicate a primary lesion in other organs. He died 12 days later. Autopsy showed multiple blood-tinged tumors in the lung but not in other organs. Cytology imprinted from 1 pulmonary tumor showed atypical cells occasionally forming small clusters and lumen-like structures. Nuclei were irregular and byperchromatic with large nucleoli. Some tumor cells showed erythrophagia in the marginal cytoplasm. Immunohistochemically, tumor cells were positive for factor VIII and CD31, lading to a diagnosis of angiosarcoma. Cytologically. it was difficult, but possible to diagnose angiosarcoma by erythrophagia.