Titanium and its alloy have many advantages such as high specific strength, excellent corrosion resistance and biocompatibility. However, it is not easy to fabricate the complex shaped parts using titanium alloy because of their poor machinability and workability. Metal injection molding (MIM) process is hoped to be a suitable technique to fabricate three dimensional complicated parts of titanium and its alloy. Although the static mechanical properties of injection molded titanium alloy compacts have been studied, there are few reports regarding the dynamic fracture characteristics. In this study, pure titanium and Ti-6Al-4V alloy compacts are fabricated by MIM process and the effects of sintering conditions on the fatigue properties are mainly investigated. By optimum sintering conditions, over 95 % of sintered densities were obtained and the fatigue endurance was 164 MPa for pure titanium and 230 MPa for Ti-6Al-4V alloy, respectively.