Abstract
A term male infant weighing 3,050 g developed necrotizing enterocolitis 2 days after birth. A perforation of the intestine occurred on the 6th day. A laparotomy was carried out for creating an enterostomy at the perforation. On the 10th day after operation, the patient developed diabetes insipidus, which was successfully managed by transnasal Desmopressin administration. The cause of diabetes insipidus seems to be a transient disorder of the neurohypophyseal axis, which is secondery to septicemia orginated form NEC.