肝胆道シンチグラフィを用いた先天性胆道閉鎖症術後における肝機能の推移に関する研究

抄録

Hepatobiliary scintigraphy with <99m>^Tc-E-HIDA was carried out in 13 patients who had undergone hepatic portoenterostomy with original Roux-en-Y for "non-correctable" type of congenital biliary atresia. In all patients, there were active bile flow and disappearance of jaundice after surgery. Elimination of <99m>^Tc-E-HIDA from the liver was slow (below 2% / min.) during the first 3 postoperative months despite of adequate bile flow. The elimination rate of the radioactive agent from the liver at the third postoperative month ranged form 2 to 3% / min. There was a delay in the elimination of the radioactive agent from the liver in those who had surgery after 70 days of age or in those who had suffered from repeated ascending cholangitis. The elimination rate of the radioactive agent from the liver after the 9th postoperative month was almost the same as those who had undergone resection of the cyst and hepatico-jejunostomy for idiopathic dilatation of the extrahepatic bile ducts (4.49 ± 0.47% / min.).