小児の外科的悪性腫瘍の予後追跡調査結果報告 : 昭和46〜55年度登録症例について II.腎芽腫の予後と治療方法との関係

抄録

Three hundred and seventy one cases of Wilms' tumor were analysed in this report. Tumor-free two-year survival rate was used for this study as in the first report. On operation, total resection and non-total resection of the primary tumor were compared in relation to age, resective method of lymph node, and the existence of distant metastasis. Under one year, and between 2 and 4 years of age, the tumor-free two-year survival rates were signicantly greater in the group of total resection. On radiotherapy, the tumor-free two-year survival rates were compared between with and without the therapy, in relation to stages. Twenty-three cases with preoperative irradiation were examined without any significance. The significance of post-operative irradiation was examined in each stage and each microscopic type. On chemotherapy, tumor-free two-year survival rates and reccurence rates were examined. In preoperative therapy, no significant results were given. In post-operative therapy, Actinomycin D, Vincristine and the combination of both were compared in various dosages. When Actinomycin D was solely given, the group with over 450 micrograms had significantly greater two-year survival rate. When the combination of Actinomycin D and Vincristine was gigen, the group with full dosage had significantly greater two-year survival rate.