We report 5 infants with Stage IV-S neuroblastoma, 3 of whom received serial observations of liver metastasis with both ultrasound (US) and CT for the last one year. Other 2 cases, who were experienced in 1977 and 1979 respectively, had unique CT patterns of liver metastasis. US is a safe, simple and very useful method to diagnose abdominal tumor and to observe the regression of the liver metastasis by repeated examinations. The liver metastasis in CT had 3 patterns; 1) diffuse, 2) large solitary, and 3) small multiple. Only one case with large solitary pattern of liver metastasis had poor prognosis. Further examination should be required whether CT patterns of liver metastasis could be one of prognostic factors in Stage IV-S neuroblastoma.
