The Journal of the Japan Society for Respiratory Endoscopy
Online ISSN : 2186-0149
Print ISSN : 0287-2137
ISSN-L : 0287-2137
A Case of Diffuse Pulmonary Hemorrhage Possibly Caused by Broad-spectrum Antibiotics
Tatsuo Naitoh
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1994 Volume 16 Issue 1 Pages 83-87

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Abstract
The patient was a 67-year-old female with subarachnoid hemorrhage. After the operation, oral food intake was difficult because of drowsiness. Broad-spectrum antibiotics for various infections were used in the postoperative period. The patient developed a bleeding tendency after the operation. On the 29th post-operative day hemoptysis and cyanosis occurred. Chest X-ray film showed a diffuse alveolar pattern in both lung fields. Bronchofiberscopic examination revealed blood in the trachea and bronchi. We diagnosed this case as pulmonary hemorrhage and cause was suspected to be hemorrhagic diathesis associated with broad-spectrum antibiotics administration. After treatment with a vitamin K preparation, pulmonary bleeding subsided and prothrombin time normalized. Although pulmonary hemorrhage caused by antibiotics is rare, it can take a serious course once it does occur. Therefore, it is necessary to carefully consider the use of antibiotics in such patients with bleeding tendencies.
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© 1994 The Japan Society for Respiratory Endoscopy
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