Lung Cancer Screening with FDG-PET

Abstract

Cancer screening with FDG-PET has increased recently but the detection rate for lung cancer is not high, and PET-negative cases are frequently seen. The detection rate in our institution was 0.22% (20 cases out of 9282 PET studies) during 4 years and half, and 40% were PET-negative cases which were found out by CT. PET-negative cases consisted of those showing GGO on CT, BAG and well differentiated adenocarcinoma, and stage I. The accumulation rate was not high even in PET-positive cases, and only 25% cases detected showed high FDG concentration. Almost all false positive cases were inflammatory diseases. The importance and issues of FDG-PET for lung cancer screening are discussed.