Synchronous Squamous Cell Carcinoma at the Carina and Gastric Adenocarcinoma with Complete Remission After Multidisciplinary Treatment

Abstract

Background. We treated a very rare case of synchronous double cancer consisting of gastric adenocarcinoma and tracheal squamous cell carcinoma. Case. A 72-year-old man presented with gastric adenocarcinoma in the lateroposterior wall of the greater curvature of the middle of the corpus and synchronous squamous cell carcinoma of the carina infiltrating the esophagus. Prior to excision of the gastric adenocarcinoma, CDDP 20 mg/day was administered for 5 consecutive days, and the tracheal carcinoma was irradiated with 60 Gy. After treatment, the tracheal carcinoma and infiltration into the esophagus disappeared completely. Gastrectomy revealed that the gastric tumor was a stage IA well differentiated tubular adenocarcinoma. After surgery, 2 courses of CBDCA + weekly PTX were conducted and 600 mg/day UFT-E was orally administered for 14 weeks. After a 3-year follow-up period, the patient was asymptomatic. Conclusion. Minimally invasive surgical procedures and treatments are considered important for synchronous double cancer. This rare case of tracheal cancer, has shown complete remission for more than 3 years after multidisciplinary treatment.