2012 Volume 34 Issue 6 Pages 564-567
Case. A 55-year-old asymptomatic woman had been found to have infiltrates on a chest X-ray film on a routine checkup examination. Six months later, she visited our hospital because of increase of the chest shadows. A chest computed tomography revealed multiple infiltrates bilaterally. Laboratory findings on admission showed elevated hepatobiliary enzymes, positive for anti-centromere antibody, but negative for anti-mitochondrial antibodies in her serum. No distinct findings of autoimmune disease were found clinically. In histological examinations, a surgical lung biopsy specimen demonstrated an organizing pneumonia pattern, and a liver biopsy specimen showed findings of nonspecific chronic hepatitis. The chest image findings and the elevated hepatobiliary enzymes improved in response to the treatment with corticosteroid. Conclusion. To the best of our knowledge, this is a rare case of organizing pneumonia associated with unclassified autoimmune liver disease.