2014 Volume 36 Issue 5 Pages 519-524
Background. Pneumonic-type adenocarcinoma (P-ADC) is known as a subtype of pulmonary adenocarcinoma, which usually shows unilateral or bilateral aerogenic dissemination. Some reports have demonstrated that various cytokines produced by cancer cells participate in fibrotic changes around the tumor. Case. A 76-year-old man was referred to our hospital with a 2-month history of dry cough. Chest computed tomography demonstrated bilateral diffuse ground-glass attenuations, consolidations, and honeycombing with traction bronchiectasis. These radiological findings were compatible with interstitial pneumonia. Bronchoscopic examination was performed, and cytology of the right middle lobe revealed adenocarcinoma, and also transbronchial lung biopsy specimens obtained from the left lung demonstrated adenocarcinoma with lepidic and papillary growth pattern. Therefore, we diagnosed this case as P-ADC with aerogenous dissemination. Conclusion. This case showed that P-ADC occasionally emerges pulmonary fibrotic changes and can resemble radiological findings of interstitial pneumonia.