JOURNAL OF THE JAPAN STATISTICAL SOCIETY
Online ISSN : 1348-6365
Print ISSN : 1882-2754
ISSN-L : 1348-6365
EFFICIENT DIRECTIONAL INFERENCE METHODOLOGIES FOR THE COMPARISONS OF THREE ORDERED TREATMENT EFFECTS
Anthony HayterTetsuhisa MiwaWei Liu
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JOURNAL FREE ACCESS

2001 Volume 31 Issue 2 Pages 153-174

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Abstract

We consider the unbalanced one-way layout for comparing 3 treatment effects which can be assumed to satisfy the simple ordering μ1 &le; μ2 &le; μ3. This problem arises often in the comparison of three dose levels in medical trials, for example. The one-sided studentised range test provides a set of simultaneous confidence intervals for the ordered pairwise differences μj - μi, i < j which are one-sided and have infinite upper bounds. The new confidence interval procedure proposed in this article maintains the sensitivity of the one-sided studentised range test in detecting each of the ordered differences μj - μi > 0 while at the same time providing two-sided finite confidence intervals. Consequently, this new procedure has the advantage of allowing the same directional inferences as the one-sided studentised range test while additionally providing upper bounds on the differences among the treatment effects.

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