We found a significant correlation between people's preference for Japanese miso and their susceptibility to mental and/or physical stress. We selected two kinds of Japanese miso, red miso and white miso. A sensory evaluation based on ANOVA revealed that miso preference significantly correlates to a mental feeling of depression (p=0.026). The feeling of depression among the examinees with a preference for red miso was lower level than that among those who had a preference for white miso. Furthermore, we attempted to classify the degree of depression into 3 levels in order to make a crosstable. Another evaluation (chi-square) on the table showed almost the same results (p=0.041). The results seem to be due to the characteristics of the ingredients of red miso.