Abstract
The ideal replacement therapy in dental extraction in patients with hemophilia should consist of the minimum but sufficient amount required. We have been pointing out the importance of local hemostatic therapy in the control of hemorrhage from the oral cavity in this disease, along with the replacement therapy. From such a viewpoint, replacement therapy conducted 101 times on 120 teeth during the last 5 years was studied.
The frequency of replacement was 2-2.5 times higher in multirooted teeth than in single rooted teeth. In those with local hemorrhage at the time of extraction versus those without, a larger dosage was given.
Comparison between cases of single extractions and multiple extractions revealed no remarkable difference. Calculation of the amount of replacement in terms of whole blood revealed on the average 556ml per one deciduous tooth and 652ml per one permanent tooth in hemophilia A, while one deciduous tooth required 368ml and one permanent tooth 748ml in hemophilia B.
