Japanese Journal of Veterinary Research
Online ISSN : 2758-447X
Print ISSN : 0047-1917
SHORT COMMUNICATION
Ability of Pasteurella canis isolated from host animals and human patients in Japan to invade human keratinocytes
associations between cell invasion ability and host or genotypic traits
Haruno YoshidaTakahiro MaedaMieko GotoYuzo TsuyukiKenichi ShizunoTakashi Takahashi
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2024 Volume 71 Issue 4 Pages 121-129

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Abstract

We examined human keratinocyte cell invasion ability (CIA) of Pasteurella canis from 17 animals and 13 humans with relationships between CIA and host/genotypic traits. We designated CIA higher than isolate mean as high-frequency and that lower than mean as low-frequency. Repetitive element-based fingerprinting dendrograms were constructed; virulence-associated genes were clustered in phylogenetic trees. High-frequency CIA was observed in 9 isolates; low-frequency CIA in 21. No relationships were observed between high-frequency CIA and host/source. Dendrograms showed no associations between high-frequency CIA/host and different clades (A–1/–2; B–1/–2/–3). Trees with ptfAompA alleles showed no associations between high-frequency CIA/host and different clusters (1/2; 1/2/3). Our observations suggest CIA assessment feasibility without relationships between high-frequency CIA and host/genotypic traits.

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© 2024 Japanese Journal of Veterinary Research Editorial Committee, Faculty of Veterinary Medicine, Hokkaido University
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