抄録
In the series of the studies on the function of the lymphocytes, the antibody producing ability is the most important one.
It is obvious that the lymph ocytes produce the complete humoral antibody as described in previous reports.
Passive tra nsfer of tuberculin hypersensitivity with various cells such as lymph nodecells, peritoneal cells, and spleen cells have been well studied by many authors.
Fukase, and Fuji succeeded in proving the passive transfer of tubercul in hypersensitivity by using thoracic duct lymphocytes. However, it seems worthwhile to accumulate further data by a repetition of this experiment, as Yasuhira has reported his critical results on this. problem.
The present report is designed to ascertain that the lymphocytes produce the cellular antibody by means of several methods, using sensitized thoracic duct lymphocytes, popliteal lymph node cells, popliteal efferent lymphocytes and peritoneal cells.
The results are as fallows:
1) Tuberculin hypersensitivi ty are transfered passively in Prausnitz-Kiistner's type by thesensitized lymphocytes.
2) The intensity of tuberculin reaction seems to be related to the number of the injected cells.
3) The sensitized peritoneal cells have a greater observable ability to induce the passivetransfer of tuberculin hypersensitivity than the sensitized lymphocytes.
4) No incomplete tuberculin antibody was detected in lymphocytes in spite of a positiveresult in serum by Middlebrook-Dubos reaction and Boyden reaction.
5) The baby rabbits transfered with either sensitized thor acic duct lymphocytes, popliteal lymph node cells, or peritoneal cells taken from tuberculin intensely positive adult rabbits. sensitized by several injections of heat killed tubercle bacilli suspended in Freund's adjuvant shawed negative tuberculin skin test. The baby rabbit is inadequate for the transfer experiment in which Prausnitz-Kiistner reaction is used.
