小児気管支喘息の減感作療法に関する臨床的研究

第1編 家屋塵エキスによる皮膚反応に関する2,3の検討

抄録

The scratch test was conducted on 127 bronchial asthmatic children who visited the Asthma Clinic in the Pediatric Department of the Kansai Medical School.
When indicated, the intracutaneous test and the Prausnitz-Kiistner test (hereafter called PK test) were conducted. Comparative studies on the results of these tests revealed the following:
1. The rate of result coincidence between the intracutaneous test and the scratch test was 73.3%. While the positive reactions obtained by the scratch test were 75.6%, those of the intracutaneous reaction were 69.3%, i. e., the scratch test showed a higher positive reaction than the intracutaneous test.
2. The rate of result coincidence between the P-K reaction and the scratch test was as high as 82.7%.
This means that the possibility of oversight is greater than six percent, and that a screening test combining both the scratch test and the P-K reaction can lessen this possibility.
3. The rate of result coincidence between the P-K reaction and the intracutaneous test was 70.8%, a rate slightly inferior to that between the scratch test and the P - K reaction. W hen screening is conducted by the intracutaneous test alone, about 20% of the cases may be overlooked. It means that the scratch test is superior to the intracutaneous test as a method of screening.
4. The rate of result coincidence among the P-K test, the scratch test and the intracutaneous tests was 66.2%. The cases which were negative to the scratch test and the intracutaneous test but positive to the P-K reaction were only 2.6%.
Therefore when former two tests are negative, it is clinically permissible to decide whether the case is allergen or not, even without conducting a P-K reaction.