Ten cases of colitis which were induced by the administration of AB-PC, AM-PC, CEX or TC + MNC and encountered during the past 2 years in our department are reported.
Chief complaint of all cases was bloody diarrhea which was preceded by watery diarrhea and associated with severe lower abdominal pain and developed within 1 to 5 days after the administration of antibiotics. Most cases had more than 10 passages a day. Bloody diarrhea lasted for 4 to 9 days and disappeared within 6 days after the discontinuation of antibiotics. No remarkable increase in ESR was observed but all cases had fever of 37.2 to 38.9°C. Colonoscopic examinations revealed the mucosal edema, redness and scattered hemorrhagic erosion at flexura lienalis to sigmoid colon. By biopsies non-specific inflammatory reactions such as congestion, hemorrhage and cell infiltration were observed.
