Abstract
Studies are made on the in vitro lysis of tuberculous patients' leucocytes due to tuberculin, which has been introduced by Favour and others.
Tuberculin diluted to 1: 480 is added to normal and tuberculous patients' leucocyte suspensions to have the respective leucocyte numbers counted.
The results obtained are as follows
1) Tuberculous patients' leucocytes show rapid cytolysis in vitro following the addition of tuberculin.
2) The cytolysis is not so marked in six normal subjects as in the tuberculous.
3) Neutrophils play a main role in the leucocytolysis, sometimes lymphocytolysis is demonstrated.
4) Severe tuberculous cases show more marked leucocytolysis than the other cases observed.
