The Journal of Medical Investigation
Online ISSN : 1349-6867
Print ISSN : 1343-1420
ISSN-L : 1343-1420
Reviews
Vitamin A and sleep regulation
Hiroyoshi Sei
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2008 Volume 55 Issue 1,2 Pages 1-8

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Abstract

Vitamin A is the parent compound of retinoids, which regulate gene transcription by binding to nuclear retinoid receptors. Recently, it has been suggested that retinoid signaling pathways are important for adult neural function in health and disease. In this mini review we will summarize the molecular pathway of retinoid and experimental data on this pathway relating to sleep regulation, which suggests that retinoid signaling mechanism may be involved in the homeostatic component of sleep electroencephalogram. J. Med. Invest. 55: 1-8, February, 2008

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© 2008 by The University of Tokushima Faculty of Medicine
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