The Journal of Medical Investigation
Online ISSN : 1349-6867
Print ISSN : 1343-1420
ISSN-L : 1343-1420
Case reports
A case of acute acalculous cholecystitis complicated by primary Epstein-Barr virus infection
Kenichi SugaMiki ShonoAya GojiSato MatsuuraMiki InoueMasami KawahitoKazuhiro Mori
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2014 Volume 61 Issue 3.4 Pages 426-429


Acute acalculous cholecystitis (AAC) is a rare complication of infectious mononucleosis (IM). An immunocompetent 6-year-old Japanese girl complained of epigastralgia during the course of IM. Ultrasonography (US) revealed a markedly thickened and sonolucent gallbladder wall. No gallstones were apparent. Antibodies against Epstein-Barr virus (EBV) confirmed primary EBV infection. Cytomegalovirus immunoglobulin M showed a false-positive result in the acute phase, probably due to cross-reaction to EBV nuclear antigen. We diagnosed her as AAC related with primary EBV infection. She recovered completely by conservative treatment. US should be performed in consideration of the possibility of AAC when a patient with IM complains of epigastralgia. J. Med. Invest. 61: 426-429, August, 2014

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© 2014 by The University of Tokushima Faculty of Medicine
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