経皮的ラジオ波焼灼療法（RFA）による組織像の経時的変化

寺谷 卓馬; 椎名 秀一朗; 今井 康雄; 小尾 俊太郎; 小池 幸宏; 浜村 啓介; 赤松 雅俊; 段 佳之; 藤島 知則; 建石 良介; 石川 隆; 白鳥 康史; 小俣 政男

doi:10.3380/jmicrowavesurg.19.43

RFA

Histological findings after Percutaneous Radiofrequency Ablation Therapy (RFA) for Hepatocellular Carcinoma (HCC)

Takuma Teratani, Shuichiro Shiina, Yasuo Imai, Shuntaro Obi, Yukihiro Koike, Keisuke Hamamura Hamamura, Masatoshi Akamatsu, Yoshiyuki Dan, Tomonori Fujishima, Rhosuke Tateishi, Takashi Ishikawa, Yasuo Shiratori, Masao Omata

Author information

Takuma Teratani
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Shuichiro Shiina
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Yasuo Imai
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Shuntaro Obi
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Yukihiro Koike
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Keisuke Hamamura Hamamura
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Masatoshi Akamatsu
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Yoshiyuki Dan
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Tomonori Fujishima
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Rhosuke Tateishi
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Takashi Ishikawa
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Yasuo Shiratori
Department of Gastroenterology, Faculty of Medicine, University of Tokyo
Masao Omata
Department of Gastroenterology, Faculty of Medicine, University of Tokyo

Keywords: RFA (radiofrequency ablation therapy), fine needle biopsies, H-E (hematoxyline-eosine) dyeing

JOURNAL FREE ACCESS

2001 Volume 19 Pages 43-46

DOI https://doi.org/10.3380/jmicrowavesurg.19.43

Details

Abstract

We performed RFA for 718 nodules in 314 HCC patients between February 1999 and October 2000. Among them, 30 nodules in 25 patients who underwent fine needle biopsies after RFA were subjects in this study. Fine needle biopsies for targeting tumor were performed mainly from one week to one month after RFA. We investigated the specimens with hematoxylin-eosine (H-E) dyeing. Before RFA, all nodules were proven HCC by biopsies. At the early stage within one week after RFA, around 30% of the nodules didn't show necrosis from specimens with H-E dyeing and had discrepancy between CT findings and them. However, one month or more later, they would be considered to progress toward the necrosis. All nodules have had no local recurrence from any images in more than one year.

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