肝細胞癌に対する内科的局所熱凝固療法の長期予後について

坂口 浩樹; 小塚 立蔵; 元山 宏行; 山口 康徳; 中屋 美香; 麻植 愛; 林 健博; 黒岡 浩子; 藤井 英樹; 小林 佐和子; 岩井 秀司; 森川 浩安; 榎本 大; 田守 昭博; 河田 則文

doi:10.3380/jmicrowavesurg.29.123

Long-term prognosis of patients with hepatocellular carcinoma who underwent thermal ablation therapies

Hiroki Sakaguchi, Ritsuzo Kozuka, Hiroyuki Motoyama, Yasunori Yamaguchi, Mika Nakaya, Ai Oe, Takehiro Hayashi, Hiroko Kurooka, Hideki Fujii, Sawako Kobayashi, Shuji Iwai, Hiroyasu Morikawa, Masaru Enomoto, Akihiro Tamori, Norifumi Kawada

Author information

Hiroki Sakaguchi
Center for Liver Diseases, Izumi Municipal Hospital
Ritsuzo Kozuka
Department of Hepatology, Graduate School of Medicine, Osaka City University
Hiroyuki Motoyama
Department of Hepatology, Graduate School of Medicine, Osaka City University
Yasunori Yamaguchi
Department of Hepatology, Graduate School of Medicine, Osaka City University
Mika Nakaya
Department of Hepatology, Graduate School of Medicine, Osaka City University
Ai Oe
Department of Hepatology, Graduate School of Medicine, Osaka City University
Takehiro Hayashi
Department of Hepatology, Graduate School of Medicine, Osaka City University
Hiroko Kurooka
Department of Hepatology, Graduate School of Medicine, Osaka City University
Hideki Fujii
Department of Hepatology, Graduate School of Medicine, Osaka City University
Sawako Kobayashi
Department of Hepatology, Graduate School of Medicine, Osaka City University
Shuji Iwai
Department of Hepatology, Graduate School of Medicine, Osaka City University
Hiroyasu Morikawa
Department of Hepatology, Graduate School of Medicine, Osaka City University
Masaru Enomoto
Department of Hepatology, Graduate School of Medicine, Osaka City University
Akihiro Tamori
Department of Hepatology, Graduate School of Medicine, Osaka City University
Norifumi Kawada
Department of Hepatology, Graduate School of Medicine, Osaka City University

Keywords: hepatocellular carcinoma, radiofrequency ablation, microwave coagulation, survival rates, laparoscopy

JOURNAL FREE ACCESS

2011 Volume 29 Pages 123-126

DOI https://doi.org/10.3380/jmicrowavesurg.29.123

Details

Abstract

We analyzed the rates of survival and local recurrence among 89 patients with solitary hepatocellular carcinoma (HCC) who underwent thermal ablation therapies as primary treatment (naive patients). The number of patients was as follows; 35 cases in percutaneous radiofrequency ablation (RFA), 5 in laparoscopic RFA, 22 in percutaneous microwave coagulation therapy (MCT), and 54 in laparoscopic MCT. Five-year local recurrence rates were 40%, 50%, 50%, and 18% in percutaneous RFA, laparoscopic RFA, percutaneous MCT, and laparoscopic MCT, respectively, with no statistical significance. Rates of 5-year survival were 78%, 75%, 82%, and 70% in percutaneous RFA, laparoscopic RFA, percutaneous MCT, and laparoscopic MCT, respectively, with no statistical significance.
Thus, percutaneous RFA, laparoscopic RFA, percutaneous MCT, and laparoscopic MCT had same effectiveness for the local treatment of HCC.

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