1991 Volume 9 Pages 23-28
For the treatment of malignat gliomas, a hyperthermia microwave probe with a water-cooling system has been developed. This system can be utilized Iseki's CT-guided stereotactic frame and has the advantage of possibility of produce useful tissue temperature of up to 42.5°C within localized thermal field of 3cm in diameter without thermal toxity to critical normal brain tissue
The new water-cooling system consists of the outer catheter with circulating water of 0-1°C, the cooling container Model 93-520 and an infusion pump. Even if the microwave antenna to be operated at 30W power, the temperature surrounding the microwave pobe was limited less 35°C that induced no definite thermal damage to normal brain tissue. The tissue temperatue was measured in three patients with malignant glioma at three points 5mm, 10mm, and 15mm from the tip of the antenna. The antenna produced useful heating field of 43°C within 3cm in diameter 7-9 minites after starting hyperthermia treatment.
Combination of the microwave probe with the water-cooling system and CT-EHO-guided stereotactic appratus could be effective in the application of microwave brain hyperthermia for malignant deep-seated brain tumors that are impossible to perform conventional surgical treatnent.
