The proposed study aims to examine the relation between the Tibetan Plateau (TP) thermal condition and El Niño and Southern Oscillation (ENSO). There were significantly positive correlations between the snow water equivalent (SWE) over the TP from November to next April and sea surface temperature (SST) in the Eastern Equatorial Pacific (EEP) in Novmber from 1987 to 2005. SST in EEP in November is most significantly correlated with the TP-SWE in next April, which suggests an accumulative effect of the ENSO on the TP snow cover. Although El Niño conditions could bring anomalous snowfall over the TP by generating a wave train entering the North African-Asian jet, it is questionable if this impact could change the thermal condition over the TP. There was almost no significant negative correlation between the SWE and TP surface temperature (representing the TP thermal condition) in winter. This suggests that the TP thermal condition hardly varies with the anomalous snowfall caused by this ENSO impact, despite some cooling effect of snowfall during the El Niño phase. On the contrary, preceding El Niño conditions tended to be associated with increasing TP surface temperature in May and there were significant positive correlations between SWE in April and TP surface temperature in May and June. ENSO might play a part in affecting TP thermal condition in a way that is quite different from the previous research. A plausible mechanism based on the relation of ENSO-TP thermal condition has been proposed. The mechanism explained the direct and indirect effects of ENSO on the TP thermal condition and role that the seasonal progress can play in this relation. The issues about snow cover aging and the impact of global warming, among others, were also included in the mechanism.