Journal of Neuroendovascular Therapy
Online ISSN : 2186-2494
Print ISSN : 1882-4072
ISSN-L : 1882-4072
FRED: Device and the State in Japan
Use of a Flow Re-direction Endoluminal Device (FRED) for Wide-neck Large/Giant Cerebral Aneurysms
Yuji MatsumaruTatsuo AmanoMasayuki Sato
著者情報
ジャーナル オープンアクセス

2017 年 11 巻 3 号 p. 153-159

詳細
抄録

Objective: There are some reports concerning the effectiveness of flow-diverter (FD) stents for untreatable cerebral aneurysm by conventional surgery and endovascular treatment. Treatment with a Pipeline embolization device, one of the original FD stents, has just started in Japan. We report herewith our initial experience of Flow Re-direction Endoluminal Device (FRED), which is a new FD with unique double layer structures, for wide-neck large or giant cerebral aneurysms.

Materials and Methods: This report is part of a clinical trial for the approval of FRED in Japan with permission of the Institutional Review Board of Toranomon Hospital. Between October 2014 and January 2015, we treated six aneurysms in six patients with FRED including three cavernous and three paraclinoid aneurysms, three asymptomatic and three symptomatic aneurysms, four large and two giant aneurysms.

Results: All patients were treated with single FRED without any coils. There were no transient ischemic attack, no stroke and no death in peri- and post-operative periods. One patient’s preexisting eye symptom temporarily worsened. Follow-up angiography at 6 months showed no filling (O’Kelly Marotta scale: D) in two patients, entry remnant (OKM scale C) in two patients, and subtotal filling (OKM scale B) in two patients.

Conclusion: Treatments using FRED were achieved without any severe complication. Clinical trials will continue to demonstrate its safety and efficacy for complex aneurysms.

著者関連情報

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
前の記事 次の記事
feedback
Top