1975 Volume 21 Issue 1 Pages 27-30
During incubation of fertilized hen egg, flavin in egg white migrated into the embryo. The total amount of flavins in the embryo increased with development. On the 7th day of incubation, molar ratio of riboflavin and flavin nucleotides in the embryo was already similar to that of animal tissues. Even though appreciable amounts of FMN and FAD were found in egg white, flavin nucleotides found in the embryo in its early embryonic life cannot be simply ascribed to the migration of these nucleotides originally present in egg white, because egg yolk contains no appreciable amount of flavin nucleotides; the possibility that flavin nucleotides are synthesized from riboflavin in the embryo in its early embryonic life still exists.