Journal of Nutritional Science and Vitaminology
Online ISSN : 1881-7742
Print ISSN : 0301-4800
ISSN-L : 0301-4800
EFFECT OF FOOD RESTRICTION ON INTESTINAL DISACCHARIDASES IN STREPTOZOTOCIN-INDUCED DIABETES OF RAT
Kazuhiko YAMADAToshinao GODAMitsuyoshi SASAKISachiko MORIUCHINorimasa HOSOYA
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1980 Volume 26 Issue 6 Pages 599-606

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Abstract

The effect of food restriction on the intestinal weight and membrane digestive enzyme activities was observed in rats with diabetes induced by streptozotocin. The specific activities of disaccharidases of food non-restricted diabetic rats were not changed, but total activities were significantly increased due to the increase of intestinal mucosal weight. Restriction of food intake did not increase intestinal mucosal weight, but significantly increased the specific and total activities of disaccharidases in parallel with the increase of sucrase-isomaltase content.
On the other hand, experimental diabetes did not influence the activity of alkaline phosphatase and leucine aminopeptidase except for specific and total activities of alkaline phosphatase in food non-restricted rats.

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