Journal of Nutritional Science and Vitaminology
Online ISSN : 1881-7742
Print ISSN : 0301-4800
ISSN-L : 0301-4800
Effects of Vitamin E in Kid Erythrocytes on Tween 20 Induced Hemolysis in vitro
Kyoko HODATETatsuo HAMADAI
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1984 Volume 30 Issue 6 Pages 509-514

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Abstract

Red blood cells (RBC) of alpha-tocopherol sufficiency and deficiency were produced in kids fed on purified diets to investigate the relationship between RBC alpha-tocopherol levels and hemolysis induced by Tween 20. RBC alpha-tocopherol contents of vitamin E-deficient kids were non-detectable from 4 weeks, and percentages of hemolysis increased to over 70%. A highly significant decrease in hemolysis was noted when vitamin E was added to the diet. Tween 20 hemolysis values were negatively correlated with RBC tocopherol levels in kids. The concentration of RBC alpha-tocopherol required to prevent the hemolysis was found to be 0.6 μg/ml packed cells.

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