Journal of the Japan Organization of Clinical Dermatologists
Online ISSN : 1882-272X
Print ISSN : 1349-7758
ISSN-L : 1349-7758
Article
A case of primary cutaneous extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
Keiko TakadaNagisa YoshiharaEtsuko KomiyamaShigaku Ikeda
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JOURNAL FREE ACCESS

2021 Volume 38 Issue 4 Pages 624-628

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Abstract

A 76-year-old Japanese male presented to our hospital with a three-month history of erythema on the left cheek and at the base of the right side of the nose. The histopathological findings of a skin biopsy from the erythema on the left cheek showed a diffuse, chromatin-rich tumour lesion in the dermis. Immunohistochemical examinations showed that the tumour cells were positive for CD20, CD79a, and Bcl-2 and negative for CD5, CD10, and Bcl-6. No immunoglobulin gene rearrangements were detected. These findings led to the diagnosis of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). There were no atypical lymphocytes in the bone marrow, and a systemic search revealed no lesions other than the skin lesions. These findings were consistent with primary cutaneous MALT lymphoma. We report a case of primary cutaneous MALT lymphoma with a review of the literature.

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© 2021 Japan Organization of Clinical Dermatologists
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