産業医学
Online ISSN : 1881-1302
Print ISSN : 0047-1879
ISSN-L : 0047-1879
n-ヘキサンの毒性と量・反応関係
竹内 康浩久永 直見小野 雄一郎井上 俊
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ジャーナル フリー

1980 年 22 巻 6 号 p. 470-487

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A large amount of n-hexane is being widely used in industry as a solvent or a component of the mixed solvents for extraction of vegitable oils, adhesives, paints, and for cleaning, etc. And, many cases of polyneuropathy due to n-hexane have been reported up to now. Recently, studies on the neurotoxicity and metabolism of n-hexane rapidly progressed in many countries. The present review covers clinical signs and symptoms, pathological changes, metabolism, dose-response (effect) in acute exposure, glue or thinner sniffers, workers, animal experiments. The joint effects and the maximal allowable concentration of n-hexane are also briefly discussed.

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© 社団法人 日本産業衛生学会
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