33 巻 (1991) 6 号 p. 485-490
It was confirmed that the function of DMSO as an inducer of cell differentiation was suppressed by co-culture of crocidolite asbestos, using the activity of protein kinase C as indicator, because DMSO reacted with ·OH radical released by stimulation with crocidolite and wasted itself. SOD inhibited the effect of crocidolite, because SOD reacted with ·O2- released by stimulation with crocidolite and inhibited the subsequent development of ·OH.