組織培養法による免疫学的研究
第3篇 リンパ球の組織培養による抗体の産生について
1956 年 68 巻 4special 号 p. 71-79
詳細
1956 年 68 巻 4special 号 p. 71-79
Of course tissue culture is best method to apply for experimental reserch on organs producing antibodies. The author, on late having been informed of the recent importance of antibodies production due to lymphocytes, conducted certain experiments about it: results were as follows;
(1) The productions of hemagglutinin, hemolysin, Forssman's antibody, bacterioagglutinin and precipitin were recognized in pure cultivated lymphocytes.
(2) Antibodies producted in pure cultivated lymphocytes had specifity against corresponding antigens.
(3) The productions of antibodies in lymphocytes reached the highest titer more rapidly compared to the titer of antibodies in blood, but decreased more rapidly too. The maximum titer of tissue antibodies proved higher than that of blood antibodies.
(4) It was recognized that precipitins are made rather in a slower degree than that of other antibodies. In case immunized antibodies prove great in quantity serum antibody value proves higher, but in case it is small in amount antibody production supersedes that of serum.
