1963 年 75 巻 11-12 号 p. 1029-1034
The general characteritics of R. tsutsugamushi which passaged on cells of tissue culture were always constant and showed the same charaçters with original physical characteristics of rickettsia. Gradually, growth of intracellular rickettsia was observed clearly and CPE was kept constantlly after passages in long period. Such CPE by R. tsutsugamushi was a infection indicator and showed a specific infection system.