Journal of Oleo Science
Online ISSN : 1347-3352
Print ISSN : 1345-8957
ISSN-L : 1345-8957
Biochemistry and Biotechnology
Synthesis and Antimicrobial Activity of Quaternary Ammonium Silane Coupling Agents
Norio YoshinoShigenori SugayaToshimitsu NakamuraYoh-hei YamaguchiYukishige KondoKazuo KawadaToshio Teranaka
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2011 Volume 60 Issue 8 Pages 429-438

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Abstract

Fourteen novel silane coupling agents with a quaternary ammonium group introduced into the molecule, [CH2=CHCH2N+(CH3)(CnH2n+1)(CH2)3Si(OCH3)3]X- (n-X, n=10–18, X=Cl, Br, or I), were synthesized with the aim of using these agents to make material surfaces antimicrobial for a long period of time. Measurements of the minimum inhibitory concentrations (MIC) against 12 kinds of fungi and bacteria revealed that the coupling agent with a C10 alkyl chain and Cl- or Br- counter-ion (10-Cl or 10-Br) has the highest antimicrobial activity among the n-X agents synthesized, but 14-Cl and 14-Br showed the highest activity on a modified porcelain plate.

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© 2011 by Japan Oil Chemists' Society
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