Studies on the Soysterol. VI.

Synthesis of 6 α-Methyl-Δ^{4, 22}-stigmastadiene-3-one

Abstract

Epoxidation of stigmasterol, followed by cleavage of the oxide with methylmagnesium iodide, oxidation of 6 β-methyl-3β, 5α-diol and hydrogen chloride dehydration of 6 β-methyl-5 α-ol-3-one afforded 6 α-methyl-Δ^{4, 22}-stigmastadiene-3-one in an over-all yield of 22%.