A Convenient Preparative Method for 1, 4-Diketones from Carboxylic Acids

Abstract

Various 1, 4-diketones were prepared from carboxylic acids via two steps : Grignard reaction with vinylmagnesium chloride and oxidation with Jones reagent catalysed by mercuric propionate. For example, 2, 5-undecanedione was prepared from heptanoic acid via 1-undecen-5-one.