抗菌性を有する界面活性剤についての研究 (第7報)
ノニルフェニル-ポリオキシエチレン-エーテル誘導体の合成と抗菌性
1979 年 28 巻 1 号 p. 31-35
詳細
1979 年 28 巻 1 号 p. 31-35
Commercial nonylphenyl poly (oxyethylene) ethers (n=3.811.0) were formylated at their benzene nucleus. The formyl derivatives (POE-CHO) obtained were then oxydized to the corresponding carboxylic acids (POE-COOH). Moreover, sodium salts (POE-COONa) and methyl esters (POE-COOCH3) of those acids were prepared. The surface tension of the aqueous solutions of POE-CHO, POE-COOH, POE-COONa and POE-COOCH3 were found to be almostly as low as those of their starting ethers. The antimicrobial and antifungal activities of those compounds were rearranged. POE-COONa and POE-COOCH3 had little or no activity at the concentration of 100μg/ml. Although POE-CHO were nonionic surface active compouds and POE-COOH depended their surface activity on the nonionic moiety of their molecules, POE-CHO and POE-COOH showed considerably antimicrobial and antifungal on bacteria and notably on some fungi, respectively.
