海洋細菌によるEPAの生産とその酵素系
1993 年 42 巻 4 号 p. 278-285
詳細
1993 年 42 巻 4 号 p. 278-285
Icosapentaenoic acid (EPA) -producing bacteria were isolated from intestinal contents of marine animals. Shewanella sp. strain SCRC-2738, which is one of the many excellent EPA-producing bacteria, was examined for EPA productivity, usefulness for our health and industrial utilization and synthetic mechanism of the EPA. The major lipids of the strain were phosphatidylethanolamine (PE) and phosphatidylglycerol (PG). The ratio of EPA were 14.6 % of total fatty acid in PE and 40.4 % of that in PG. The maximum EPA productivity was 376.4 mg/L culture broth.
The strain incorporates exogenous docosahexaenoic acid (DHA) into phospholipids without a change of the endogenous EPA productivity. It is possible that the strain synthesize EPA via pathway different from those of higher plants and algae, although the enzyme participated the pathway is still unknown in detail.
