Genetic study of gutter-shaped root (GSR) in AKXL RI mouse strains using QTL analysis

Itaru Tashima; Koichiro Arita; Yoshinobu Asada

doi:10.2334/josnusd.52.213

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Genetic study of gutter-shaped root (GSR) in AKXL RI mouse strains using QTL analysis

Itaru Tashima, Koichiro Arita, Yoshinobu Asada

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Keywords: AKXL RI mice, Gutter-shaped root, QTL analysis, dental root fusion rate

JOURNAL FREE ACCESS

2010 Volume 52 Issue 2 Pages 213-220

DOI https://doi.org/10.2334/josnusd.52.213

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Abstract

In this study, quantitative trait locus (QTL) analysis was used to identify candidate chromosomes and for detecting the regions that include the gene or genes causing gutter-shaped root (GSR) in AKXL recombinant inbred mouse strains. One potential QTL was detected on chromosome 5 within a region of 13.0 cM, where the likelihood ratio statistic (LRS) score was higher than a suggestive level. This indicates that one of the candidate genes causing mouse GSR may be located in this region. (J Oral Sci 52, 213-220, 2010)

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