Journal of Oral Science
Online ISSN : 1880-4926
Print ISSN : 1343-4934
ISSN-L : 1343-4934
Case Report
Oral soft-tissue angiolipoma: report of two cases of rare oral lipomatous lesion with emphasis on morphological and immunohistochemical features
Geraldo O. Silva-JuniorBruna L. PiccianiRaphael C. CostaSaulo M. BarbosaMarcelo G. SilvaresRamiro B. SouzaMarília H. CantisanoFabio R. Pires
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2013 Volume 55 Issue 1 Pages 85-88

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Abstract

Oral angiolipomas are exceedingly rare and little is known about their morphological and etiological features. Here, we report two cases of oral angiolipoma and discuss their clinicopathological and immunohistochemical features, focusing on endothelial markers. Both lesions presented mature adipocytes interspersed by small blood vessels containing fibrin thrombi. Immunohistochemical analysis showed numerous mast cells and expression of CD34, vascular endothelial growth factor, intercellular adhesion molecule-1, interferon-γ and interleukin 6 in most endothelial and stromal cells. Mast cell-endothelial cell interaction may be responsible for the reactive or neoplastic origin of the vascular proliferation of these entities. (J Oral Sci 55, 85-88, 2013)

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© 2013 by Nihon University School of Dentistry
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