Journal of Oral Science
Online ISSN : 1880-4926
Print ISSN : 1343-4934
Original
Prefrontal cortex activity during swallowing in dysphagia patients
Jun LeeChisato YamateMasato TairaMasamichi ShinodaKentaro UrataMitsuru MarunoReio ItoHiroto SaitoNobuhito GionhakuToshimitsu IinumaKoichi Iwata
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2018 Volume 60 Issue 3 Pages 329-335

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Abstract

Prefrontal cortex activity is modulated by flavor and taste stimuli and changes during swallowing. We hypothesized that changes in the modulation of prefrontal cortex activity by flavor and taste were associated with swallowing movement and evaluated brain activity during swallowing in patients with dysphagia. To evaluate prefrontal cortex activity in dysphagia patients during swallowing, change in oxidized hemoglobin (z-score) was measured with near-infrared spectroscopy while dysphagia patients and healthy controls swallowed sweetened/unsweetened and flavored/unflavored jelly. Total z-scores were positive during swallowing of flavored/unsweetened jelly and negative during swallowing of unflavored/sweetened jelly in controls but negative during swallowing of sweetened/unsweetened and flavored/unflavored jelly in dysphagia patients. These findings suggest that taste and flavor during food swallowing are associated with positive and negative z-scores, respectively. Change in negative and positive z-scores may be useful in evaluating brain activity of dysphagia patients during swallowing of sweetened and unsweetened food.

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© 2018 by Nihon University School of Dentistry
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