Abstract
Immunoglobulin estimations by the single radial diffusion technique were performed using serum from 100 subjects comprising 50 patients with recurrent aphthous stomatitis, 25 with Behçet's syndrome and 25 normal controls. The data were subjected to multivariate analysis methods including Hotelling T2 statistics and the Roy-Bose simultaneous confidence interval. Raised levels of IgA and IgM were found in patients with recurrent aphthous stomatitis in comparison with normal controls, but there was no difference in IgG. In Behçet's syndrome, only the IgM titers showed a difference, IgG levels being insignificant.