Dataset for proteome analysis of dried blood spot by DIA-MS

Abstract

To analyse deep protein profiling of dried blood spot (DBS). We developed a simple method using sodium carbonate precipitation (SCP). SCP enriches hydrophobic proteins from DBS, allowing substantial removal of soluble proteins. In combination with SCP, we used quantitative LC-MS/MS proteome analysis in a data-independent acquisition mode (DIA) to enhance the sensitivity and quantification limits of proteome analysis.